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In female volunteers receiving long-term ethinyl estradiol provigil ms fatigue, administration of modafinil 200 mg daily for 7 days followed by 400 mg daily for an additional 21 days resulted in mean decreases of 11 and 18% in the peak concentrations and area under the plasma concentration-time curve AUC respectively, of ethinyl estradiol.The majority of cases occurred within 1-5 weeks after initiation of therapy; however, isolated cases also have been reported after prolonged treatment e.

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You should not use modafinil if you have ever had an allergic reaction or skin rash while taking modafinil or armodafinil Nuvigil Modafinil can cause skin reactions that may be severe enough to need treatment in a hospital. Stop taking this medicine and get emergency medical help if you have a skin rash or hives, blisters or peeling, mouth sores, provigil ms fatigue modafinil cognitive effects or swallowing, fever, swelling in your legs, dark urine, yellowing of your skin or eyes, or swelling in your face.After that, it takes about 3 - 7 days for the tolerance to be reduced to half and 1 - 2 weeks to be back at baseline in the provigil ms fatigue of further consumption Modafinil may present a cross-tolerance with all benzhydryl nootropics, meaning that after the consumption of modafinil, all related eugeroic compounds such as armodafinil and adrafinil will display a reduced effect.

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