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Links to sites outside of Pfizer Medical Information are provided as a resource to the viewer.A high rate of drug discontinuance generally has been observed among sildenafil fors raynauds disease receiving combination therapy with sildenafil and riociguat; at least one death, possibly related to the combined use of these drugs, has been reported. Because of the risk of hypotension, concomitant use of sildenafil and riociguat is contraindicated.

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For detailed reconstitution instructions, see Full Prescribing Information.Sildenafil should be used with caution in patients with retinitis pigmentosa, a retinal disorder that may be accompanied by a genetic disorder of retinal phosphodiesterases in some patients, since data establishing the safety and revatio for raynauds of the drug in these patients currently are lacking. Pending accumulation of such data, other clinicians suggest that sildenafil not be used at all in these revatio fors raynauds or be used revatio for raynauds particular or extreme caution and at the lowest possible dose; such precautions also have been suggested for patients with other retinal conditions such as macular degeneration or diabetic retinopathy.

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