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Times the MRHD based on BSA comparison Studies in hairless albino mice suggest that concurrent exposure to tretinoin may enhance the tumorigenic potential of carcinogenic doses of UVB and Strongest retin a available light from a solar simulator.4 Dermal carcinogenicity testing has not been performed with Retin-A Micro tretinoin Gel microsphere.
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Patients who may be subjected to considerable sun exposure because of their occupation and those with inherent sensitivity to the sun should be especially cautious; when exposure cannot be avoided, use of sunscreen products and protective clothing over treated areas may be prudent.You should also avoid using other skin products on the treated area for at least 1 hour.
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Minimize exposure to the sun and to extreme cold or wind.If exposure to the sun is unavoidable, usea sunscreen with minimum SPF 15 and wear protective clothing.
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Pediatric Usage: Safety and effectiveness in children below the age of 12 years have not been established.Topical tretinoin in animal teratogenicity tests has generated equivocal results.
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Before applying, clean and dry the skin area to be treated.Use of moisturizers concomitantly at night to counteract the drying effects of tretinoin may dilute the therapeutic effect of the drug; therefore, some clinicians suggest that moisturizers be used during the day in an attempt to minimize such potential strongest retin a.
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To do so may cause irritation of the skin.It is advised that Treclin is not be used by women who are breastfeeding. Reproduction studies in rats and mice, using subcutaneous and oral doses of clindamycin, revealed no evidence of impaired fertility.
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