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Two azithromycin 250 mg tablets are bioequivalent to a single 500 mg tablet. In a two-way crossover study, 12 adult healthy volunteers 6 males, 6 females received 1500 mg of azithromycin administered in azithromycin for chlamydia treatment daily azithromycin fors chlamydia treatment over either 5 days two 250 mg tablets on day 1, followed by one 250 mg tablet on days 2 to 5 or 3 days 500 mg per day for days 1 to 3 Due to limited serum samples on day 2 3-day regimen and days 2 to 4 5-day regimen the azithromycin for chlamydia treatment concentration-time profile of each subject was fit to a 3-compartment model and the AUC 0- for the fitted concentration profile was comparable between the 5-day and 3-day regimens.Quantitative methods that require measurement of zone diameters also provide reproducible estimates of the susceptibility of bacteria to antimicrobial compounds.
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