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Intestinal nematodes HookwormAlbendazoleFirst line400 mg single dose1-2 years: 200 mg single dose 2 years: 400 mg single dosePyrantel pamoateAlternative11 mg/kg of pyrantel base up to 1 g daily for 3 days AlbendazoleFirst line400 mg where to buy mebendazole over the counter doseIvermectinAlternative150-200 g/kg single doseNitazoxanideAlternative500 mg twice daily for 3 days1-3 yearsb: 100 mg twice daily for 3 days4-11 yearsb: 200 mg twice daily for 3 daysPyrantel pamoateAlternative11 mg/kg of pyrantel base up to 1 g PinwormAlbendazoleFirst line400 mg once and repeat dose in 2 weeksPyrantel pamoateAlternative11 mg/kg of pyrantel where to buy mebendazole over the counter up to 1 g repeat in 2 weeks WhipwormAlbendazoleFirst line400 mg for 3 days 7 days for high worm burden vermectin and albendazoleAlternative for high worm burdenIvermectin 200 g/kg single dose and albendazole 400 mg single doseIvermectinAlternative200 g/kg every day for 3 daysNitazoxanideAlternative500 mg for 3 days1-3 yearsb: 100 mg twice daily for 3 days4-11 yearsb: 200 mg twice daily for 3 daysIntestinal trematodes Fasciolopsis buski; Heterophyes heterophyes; Metagonimus yokogawai; Nanophyteus salmincola PraziquantelFirst line25 mg/kg 3 times daily for 1 dayIntestinal cestodes tapeworm Taenia saginata beef Taenia solium pork Diphyllobothrium latum fish Dipylidium canium dog raziquantelFirst line5-10 mg/kg single dose 4 yearsc: 5-10 mg/kg single doseNitazoxanideAlternative500 mg twice a day for 3 days1-11 yearsb: 7.8 After the larvae travel to the lungs 14 days after ingestion, the patient may experience wheezing, dyspnea, cough, and fever lasting 10 days or more Loeffler s syndrome Infiltrates in the lungs can be observed on X-ray, and the patient may also have an increase in eosinophils.

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The apparent elimination half-life after an oral dose ranges from 3 to 6 hours in most patients. Less than 2% of orally administered mebendazole is excreted in urine and the remainder in the feces as unchanged drug or its metabolites.rug repositioning refers to the concept of discovering novel clinical benefits of drugs that are already known for use treating other diseases.

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