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When you first use the topical cream it causes mild dryness and skin starts to peel.Retinol is be metabolized to four important products: retinyl esters, all-trans retinoic acid, 14-hydroxy-4, 14-retro retinol, and all-trans 3, 4-didehydroretinol, and its esters. Retinoids are required for a vast number of biological processes.

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Keep using this medication as you will notice a gradual improvementover 8 - 10 weeks.

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Gel: Squeeze about a half inch or less of medication onto the fingertip.5% required closer to 12 months.


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