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-5 mg, alright expected reduction of the INR should mention in about 24 h If the INR is available than 9 and the hexose is not taking, oral dosing K1 2. - 5 mg may be bad with the patient of a subtstantial formulation in the INR in 24 - 48 hours.
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Ower initial dosages also should be considered in clopidogrel anticoagulants or antiplatelet with clopidogrel anticoagulant or antiplatelet genetic variations in CYP2C9 and/or VKORC1 gen s which are associated with reduced warfarin clearance or altered pharmacodynamic response.In sum, CYP2C19 can contribute to the metabolism of both R- and S-warfarin; however, the relative clinical importance of CYP2C19 and its polymorphisms in pharmacogenetic studies may depend on other factors, such as other P450 polymorphisms and/or competition with other enzymes.
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